Glial Endozepines Inhibit Feeding-Related Autonomic Functions by Acting at the Brainstem Level
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Glial Endozepines Inhibit Feeding-Related Autonomic Functions by Acting at the Brainstem Level
Endozepines are endogenous ligands for the benzodiazepine receptors and also target a still unidentified GPCR. The endozepine octadecaneuropeptide (ODN), an endoproteolytic processing product of the diazepam-binding inhibitor (DBI) was recently shown to be involved in food intake control as an anorexigenic factor through ODN-GPCR signaling and mobilization of the melanocortinergic signaling pat...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2017
ISSN: 1662-453X
DOI: 10.3389/fnins.2017.00308